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Appendix H Biotin Interference in Diagnostic Tests
Biotin Interference in Diagnostic Tests
References
FDA (Biotin) Safety Communication 2019
National Institutes of Health. Biotin fact sheet for consumers
Roche Diagnostics. Biotin facts
The University of Iowa, Department of Pathology, Laboratory Services Handbook: Serum folate
Test List
User's Guide Name
Test Mnemonic
Test Order Number
ACTH by Immunohistochemistry
ACTH IHC
2003427
Adrenocorticotropic Hormone
ACTH
70010
Adrenocorticotropic Hormone Stimulation, 30 Minutes
CORTISOL30
70032
Adrenocorticotropic Hormone, IVC1
ACTH IVC1
70279
Adrenocorticotropic Hormone, LP1
ACTH LP1
70300
Adrenocorticotropic Hormone, RP1
ACTH RP1
70311
Alpha-1-Antichymotrypsin (A1ACT) by Immunohistochemistry
A1 ACT IHC
2003418
Alpha-1-Antitrypsin (AAT) by Immunohistochemistry
A1 AT IHC
2003424
Alpha-1-Fetoprotein (AFP) by Immunohistochemistry
AFP IHC
2003436
Amphiphysin Antibody, IgG
AMPHIPHYS
2008893
Anti-Human Epithelial Antigen, Ber-EP4 by Immunohistochemistry
BEREP4 IHC
2003463
Aquaporin-4 Receptor Antibody
AQP4
2003036
Aquaporin-4 Receptor Antibody by ELISA with Reflex to Aquaporin-4 Receptor Antibody, IgG by IFA
AQP4 R
2013327
Autoimmune Liver Assessment w/ Reflx
AUTO LIVER
2010850
Autoimmune Neuromuscular Junction Reflexive Panel
MUWA R PAN
2005640
Beta-hCG, Quantitative (Tumor Marker)
BHCG TM
70029
Beta-hCG, Quantitative (Tumor Marker), CSF
BHCG CSF
20730
Breast 2 (GCDFP-15) by Immunohistochemistry
BRST2 IHC
2003472
Breast Carcinoma b72.3 by Immunohistochemistry
B72.3 IHC
2003445
C1-Esterase Inhibitor Functional
C1 INH F
50141
C-1-Esterase Inhibitor Panel
C1 INH PAN
50139
C4D by Immunohistochemistry
C4D IHC
2003475
Cancer Antigen 125
CA125
80462
Cancer Antigen-Breast (CA 15-3)
CA-BREAST
80464
Cancer Antigen-GI (CA 19-9)
CA-GI
80461
Cancer Antigen-GI (CA 19-9), Body Fluid
CA-GI FL
20746
Carcinoembryonic Antigen
CEA
80080
Carcinoembryonic Antigen, Fluid
CEA FL
20742
Carcinoembryonic Antigen, Polyclonal (CEA P) by Immunohistochemistry
CEA P IHC
2003827
CD123 by Immunohistochemistry
CD123 IHC
2003809
CD1a by Immunohistochemistry
CD1A IHC
2003502
CD21 (Dendritic Cell) by Immunohistochemistry
CD21 IHC
2003535
CD23 by Immunohistochemistry
CD23 IHC
2003541
CD31 by Immunohistochemistry
CD31 IHC
2003550
CD34, QBEnd/10 by Immunohistochemistry
CD34 IHC
2003556
CD35 by Immunohistochemistry
CD35 IHC
2003559
CD4 by Immunohistochemistry
CD4 IHC
2003511
CD42b by Immunohistochemistry (Temporary Referral as of 08/22/2017)
CD42b IHC
2003565
CD43, L60 (Leu 22) by Immunohistochemistry
CD43 IHC
2003568
CD61 (Platelet Glycoprotein IIIA) by Immunohistochemistry
CD61 IHC
2003595
CD79A by Immunohistochemistry
CD79A IHC
2003800
Collagen IV by Immunohistochemistry
COLL 4 IHC
2003839
Cotinine Screen, Urine
COTININE
2007081
C-Telopeptide, Beta-Cross-Linked, Serum
CTX
70416
CYFRA 21-1 (Cytokeratin 19 Fragment), Serum
CYFRA
81344
Cytokeratin 20 (CK 20) by Immunohistochemistry
CYTO20 IHC
2003848
Cytokeratin 8,18 Low Molecular Weight (CAM 5.2) by Immunohistochemistry
CAM5.2 IHC
2003493
Cytokine Panel
CYT 12 SE
51394
Cytokine Panel, Monokines
CYT MON SE
51524
Cytokine Panel, TH1
CYT TH1 SE
51408
Cytokine Panel, TH2
CYT TH2 SE
51518
Cytokine Production by Mononuclear Cells in Response to Antigen and Mitogen Stimulation
CYT AM
2013111
Dehydroepiandrosterone Sulfate, Serum
DHEAS
70040
E-Cadherin by Immunohistochemistry
ECADH IHC
2003869
Epithelial Membrane Antigen (EMA) by Immunohistochemistry
EMA IHC
2003872
Epstein-Barr Virus (EBV) by in situ Hybridization, Paraffin
EBV ISH
2002902
Estrogen Receptor (ER) by Immunohistochemistry
ER IHC
2004516
Ewing Sarcoma (O13) by Immunohistochemistry
O13 IHC
2004055
Fetal Fibronectin
FFN
82024
Fibrillarin (U3 RNP) Antibody, IgG
U3 FIB
2012173
FIBRINOGEN by IF Technical Only (Bill Only, for Internal Use Only)
FIBR IFT
2005397
Follicle Stimulating Hormone, Serum
FSH
70055
Gastrin
GAST
70075
Gastrin by Immunohistochemistry
GASTRI IHC
2003896
Gastrin, 1 Minute
GAST 1
2012636
Gastrin, 10 Minute
GAST 10
2012734
Gastrin, 2 Minute
GAST 2
2012638
Gastrin, 30 Minute
GAST 30
2012736
Gastrin, 5 Minute
GAST 5
2012732
Gastrin, Baseline
GAST BASE
2012738
Glial Fibrillary Acidic Protein (GFAP) by Immunohistochemistry
GFAP IHC
2003899
Glycophorin A by Immunohistochemistry
GLYC A IHC
2003908
Granzyme B by Immunohistochemistry
GRANZB IHC
2007173
Hairy Cell Leukemia, DBA.44 by Immunohistochemistry
DBA 44 IHC
2003860
Hepatitis A Virus Antibodies (Total)
HAVAB
20591
Hepatitis A Virus Antibody, IgM
HAVABM
20093
Hepatitis A Virus Panel
HEP A PAN
20597
Hepatitis B Virus (HBV) Perinatal Exposure Follow-up by CIA, Panel
HBV PAN PN
2014285
Hepatitis B Virus Core Antibodies (Total)
HBCAB
20091
Hepatitis B Virus Core Antibody, IgM
HBCABM
20092
Hepatitis B Virus Panel, Chronic with Reflex to HBsAg Confirmation
HEPCHRONIC
20454
Hepatitis B Virus Surface Antibody
HBSAB
20090
Hepatitis B Virus Surface Antigen Confirmation, Prenatal
HBSAGCONPN
2007575
Hepatitis B Virus Surface Antigen with Reflex to Confirmation
HBSAG
20089
Hepatitis B Virus Surface Antigen with Reflex to Confirmation, Prenatal
HBSAG PN
2007573
Hepatitis B Virus Surface Antigen, Confirmation
HBSAG CONF
20128
Hepatitis C Virus Antibody by CIA
HCV AB
2002483
Hepatitis C Virus Antibody by CIA with Reflex to HCV by Quantitative PCR
HCV AB QR
2010784
Hepatitis Panel, Acute with Reflex to HBsAg Confirmation
HEP ACUTE
20457
Hepatocyte Specific Antigen (HSA) by Immunohistochemistry
HEP SA IHC
2003923
Histoplasma Antigen by EIA, Serum
HISTOAG S
92522
Histoplasma Galactomannan Antigen Quantitative by EIA, Urine
HISTOGM U
2009418
Human Chorionic Gonadotropin (Beta-hCG) by Immunohistochemistry
HCG IHC
2003920
Human Epididymis Protein 4 (HE4)
HE4
2003020
Human Immunodeficiency Virus (HIV) Combo Antigen/Antibody (HIV-1/O/2) by CIA with Reflex to HIV-1/HIV-2 Antibody Differentiation, Supplemental
HIVAGABGE
2013333
Human Immunodeficiency Virus (HIV) Combo Antigen/Antibody (HIV-1/O/2) by CIA, Reflexive Panel
HIV PANEL
2012674
Human Immunodeficiency Virus (HIV) Combo Antigen/Antibody (HIV-1/O/2) by CIA, with Reflex to HIV-1 Antibody Confirmation by Western Blot
HIV AGAB
2006526
Human Immunodeficiency Virus Type 1 (HIV-1) Antibody by CIA with Reflex to HIV-1 Antibody Confirmation by Western Blot
HIV 1 SCRN
2005375
Human Immunodeficiency Virus Types 1 and 2 (HIV-1, HIV-2) Antibodies by CIA with Reflex to HIV-1 Antibody Confirmation by Western Blot
HIV1,2 SCR
2005377
Human Papillomavirus (HPV) Low Risk by in situ Hybridization, Paraffin
HPVLOW ISH
2002896
Human Papillomavirus (HPV), High Risk by in situ Hybridization, Paraffin
HPVHI ISH
2002899
Human Placental Lactogen (HPL) by Immunohistochemistry
HPL IHC
2003938
Immunoglobulin A (IgA) by Immunohistochemistry
IGA IHC
2003957
Immunoglobulin D (IgD) by Immunohistochemistry
IGD IHC
2003960
Immunoglobulin M (IgM) by Immunohistochemistry
IGM IHC
2003966
Influenza A Virus H1/H3 Subtype by PCR with Reflex to H1N1 (2009) Oseltamivir Resistance by Sequencing
FLUTYPE RE
2008788
Inhibin by Immunohistochemistry
INHIBI IHC
2003969
Interferon gamma
IFNG DO
51531
Interleukin 1 beta
IL1B DO
51536
Interleukin 10
IL10 DO
51534
Interleukin 12
IL12 DO
51530
Interleukin 13
IL13 DO
51535
Interleukin 17
IL17
2013115
Interleukin 2
IL2 DO
51588
Interleukin 2 Receptor (CD25), Soluble
IL2R DO
51529
Interleukin 4
IL4 DO
51532
Interleukin 5
IL5 DO
51533
Interleukin 6
IL6 DO
51537
Interleukin 8
IL8 DO
51538
Kappa Light Chains by Immunohistochemistry
KAPPA IHC
2003981
Kappa/Lambda Light Chain Panel by in situ Hybridization, Paraffin
K/L ISH
2002888
Keratin 903 (K903) High Molecular Weight by Immunohistochemistry
K903 IHC
2003978
Ki-67, MIB-1, by Immunohistochemistry
MIB1 IHC
2004519
Lambda Light Chains by Immunohistochemistry
LAMBDA IHC
2003984
Liver Cytosolic Antigen Type 1 (LC-1) Antibody, IgG
LC-1
2010711
Luteinizing Hormone and Follicle Stimulating Hormone
LH/FSH
70193
Luteinizing Hormone, Serum
LH
70093
Lysozyme (Muramidase) by Immunohistochemistry
LYSOZY IHC
2003990
Mannose Binding Lectin
MBL
51692
Mast Cell Tryptase by Immunohistochemistry
MASTCT IHC
2003993
Muscle-Specific Actin (MSA) by Immunohistochemistry
MUSA IHC
2004011
Myeloperoxidase (MPO) by Immunohistochemistry
MYELOP IHC
2004014
Myoglobin by Immunohistochemistry
MYOGL IHC
2004031
Myoglobin, Serum
MYOG-S
20224
Myoglobin, Urine
MYOG-U
20223
Myosin by Immunohistochemistry
MYOSIN IHC
2004034
Neurofilament by Immunohistochemistry
NEUROF IHC
2004049
Neuron Specific Enolase
NSE
98198
Neuron Specific Enolase, CSF
NSE CSF
81226
Neuron Specific Enolase, Polyclonal (NSE P) by Immunohistochemistry
NSE IHC
2004052
Neuronal Abs (Hu, Ri, Yo, Amphiphysin)
NEURONAL
51090
Neuronal Nuclei (NeuN) by Immunohistochemistry
NEUN IHC
2004046
New York Human Immunodeficiency Virus (HIV) Combo Antigen/Antibody (HIV-1/O/2), Reflexive Panel
NY HIV PAN
2014211
Osteocalcin by Electrochemiluminescent Immunoassay
OSTEO NMID
20728
p21 (Waf1/Cip 1) by Immunohistochemistry
P21 IHC
2004067
p53 by Immunohistochemistry
P53 IHC
2004522
Pan Cytokeratin (AE1,3) by Immunohistochemistry
AE1,3 IHC
2003433
Pancreatic Elastase, Fecal by ELISA
PAN-ELAST
80526
Paraneoplastic Reflexive Panel
PNS PAN
2013955
Parathyroid Hormone, Fine Needle Aspiration (FNA)
PTH FNA
2001491
Parathyroid Hormone, Intact
PTH-INT
70346
Parathyroid Hormone, Intact with Calcium
PTHI
70172
PAX8 by Immunohistochemistry
PAX8 IHC
2010787
PD-1 by Immunohistochemistry
PD1 IHC
2004085
Placental Alkaline Phosphatase (PLAP) by Immunohistochemistry
PLAP IHC
2004097
PM/Scl-100 Antibody, IgG by Immunoblot
PM/SCL
2003040
Prenatal Reflexive Panel
PRENATAL A
95044
proBrain Natriuretic Peptide, NT
PRO BNP
50083
Progesterone Receptor (PR) by Immunohistochemistry
PR IHC
2004525
Prolactin by Immunohistochemistry
PROLAC IHC
2004109
Prostate Specific Antigen, Free Percentage (Includes Free PSA and Total PSA)
PSA FP
80206
Prostate Specific Antigen, Total
PSA
70121
Prostate Specific Antigen, Total - Medicare Screening
PSA SCN
70234
Prostate Specific Antigen, Total with Reflex to Free PSA (Includes Free Percentage)
TPSAR
80264
Prostate Specific Antigen, Ultrasensitive
PSA ULTRA
98581
Prostatic Acid Phosphatase (PAP) by Immunohistochemistry
PAP IHC
2004079
Reflexed to Free PSA (Includes Free Percentage)
BILL PSAFR
50338
Risk of Ovarian Malignancy Algorithm
ROMA
2012618
S100B CSF
2013358
S-100B Protein, Serum
S 100B
2001766
Sex Hormone Binding Globulin
SHBG
99375
Smooth Muscle Actin (SMA) by Immunohistochemistry
SMA IHC
2004130
Surgical Pathology Tissue
SP REQUEST
8090010
Systemic Sclerosis Comprehensive Panel
SCL COMP
2013325
T3 Uptake
T3 UP
70135
T-cell Intracytoplasmic Antigen (TIA-1) by Immunohistochemistry
TIA1 IHC
2004148
TdT by Immunohistochemistry
TDT IHC
2004142
Testosterone Free, Adult Male
FREE T2
70111
Testosterone, Adult Male
TESTOS
70130
Testosterone, Bioavailable and Sex Hormone Binding Globulin (Includes Total Testosterone), Adult Male
BIO T
70102
Testosterone, Free and Total (Includes Sex Hormone Binding Globulin), Adult Male
FREE T
70109
Thyroglobulin Antibody
ATHYG
50105
Thyroid Antibodies
THYRO
50645
Thyroid Peroxidase (TPO) Antibody
AMICR
50075
Thyroid Stimulating Hormone
TSH
70145
Thyroid Stimulating Hormone Receptor Antibody (TRAb)
TR AB
2002734
Thyroid Transcription Factor (TTF-1) by Immunohistochemistry
TTF1 IHC
2004166
Thyroxine
T4
70140
Thyroxine, Free (Free T4)
FT4
70138
Toll-Like Receptor Function
TLR
51589
Toxoplasma gondii by Immunohistochemistry (Temporary Referral as of 08/22/2017)
TOXOPL IHC
2004157
Transforming Growth Factor beta, Plasma
TGFB PLA
51690
Transforming Growth Factor beta, Serum
TGFB SER
51694
Triiodothyronine, Free (Free T3)
FT3
70133
Triiodothyronine, Total (Total T3)
T3 TOTAL
70474
Troponin T (cTnT) 5th Generation
CTNT
3001831
Tumor Necrosis Factor - alpha
TNFA DO
51539
Vitamin D, 1, 25-Dihydroxy
VIT D 1,25
80385